Which condition is a likely consequence of severe selenium deficiency affecting mood?

Severe selenium deficiency is associated with various mood disturbances, with depression being one of the most notable consequences. Selenium is an essential trace mineral that plays a critical role in brain function, primarily through its antioxidant properties and involvement in thyroid hormone metabolism. A deficiency can lead to oxidative stress, affecting neurotransmitter systems and mood regulation, which may contribute to the development of depressive symptoms.

Research supports the idea that adequate selenium levels are important for mental health, and low levels have been correlated with an increased risk of depression. As such, depression is often highlighted as a key mood disorder that can result from severe selenium deficiency. This highlights the importance of nutrition in mental health, where deficiencies in certain nutrients can lead to significant mood-related issues.