Which class of medication is commonly prescribed for managing GERD and PUD?

Proton pump inhibitors (PPIs) are the primary class of medication prescribed for managing gastroesophageal reflux disease (GERD) and peptic ulcer disease (PUD). PPIs work by blocking the proton pump in the stomach lining, which is responsible for secreting gastric acid. By reducing the amount of acid produced, PPIs effectively decrease gastric acidity, facilitating healing of the esophagus in GERD and promoting healing of ulcers in PUD.

The use of PPIs is particularly beneficial in conditions where excessive acid production contributes to symptoms and complications. In GERD, this reduction in acidity helps alleviate symptoms like heartburn and protects the esophageal mucosa from damage. In the context of PUD, PPIs aid in the healing of gastric and duodenal ulcers and help mitigate pain associated with these conditions.

Other classes of medications, such as antihypertensives, beta blockers, and analgesics, do not address the underlying issues of excessive gastric acid secretion and are therefore not utilized for the management of GERD or PUD.