When are vasopressors indicated in a clinical setting?

Vasopressors are indicated primarily in cases of hypotension, particularly when the mean arterial pressure (MAP) falls below a critical threshold. The guideline that MAP should be maintained above 60 mmHg is based on the need to ensure adequate perfusion to vital organs. When the MAP drops from baseline by more than 30 mmHg, this signifies a significant decline in perfusion, which can lead to organ dysfunction. Therefore, the administration of vasopressors is essential in these scenarios to restore hemodynamic stability and improve blood flow to critical organs.

In contrast, elevated heart rate alone or the presence of hyperglycemia and fever do not directly warrant the use of vasopressors. While these conditions may affect a patient’s overall clinical status, they do not necessarily indicate immediate actionable hypotension where vasopressors would be indicated. Thus, option B correctly identifies the clinical context in which vasopressors are utilized to support hemodynamics effectively.