What are the typical lab values associated with Hemophilia A?

Hemophilia A is a genetic disorder characterized by a deficiency in clotting factor VIII, which is essential for proper blood coagulation. The laboratory values typically associated with this condition include a normal platelet count, a normal prothrombin time (PT), and a prolonged activated partial thromboplastin time (aPTT).

A normal platelet count indicates that the number of platelets, which play a crucial role in blood clotting, remain unaffected in hemophilia A. The PT is normal because this pathway of blood coagulation is not primarily impacted by the deficiency in factor VIII; it mainly involves the extrinsic and common pathways, which are intact. However, because hemophilia A specifically affects the intrinsic pathway that relies on factor VIII, the aPTT is prolonged. This reflects the delay in clot formation due to the lack of adequate factor VIII activity.

Thus, the choice that states normal platelet count, normal PT, and prolonged aPTT accurately describes the laboratory findings in patients with hemophilia A, aligning with the pathophysiology of the condition.